The GMP mark of the Ministry of Food and Drug Safety signifies that the manufacturing process, from the acquisition of raw materials to production, packaging, and distribution, adheres to stringent standards for the production of excellent health functional foods. These standards are checked at every step of the entire process, covering not only the manufacturing structure and equipment but also the quality and safety of the raw materials.

It comprises a set of standards that concretize numerous requirements for the production of top-tier food and pharmaceutical products. These standards are applicable across the spectrum of quality management, from the procurement of raw materials to the final product distribution. The objective is to produce high-quality, safe food and pharmaceutical products with a heightened level of stability by eliminating intentional errors and minimizing contamination that might arise during the manufacturing process. This is achieved through the utilization of modern, automated production facilities and rigorous process management.

The newly established Health Functional Food Act allows for the labeling of functionality, distinguishing it from traditional health supplements. This change has raised consumer expectations for those who consume health functional foods. Consequently, quality control of functional components and the management of safety elements have become pivotal aspects. Unlike the traditional product management approach, where sole reliance on final product specifications leads to challenging quality assurance for health functional foods, every aspect of production and quality control, from raw materials to the release of the final product, is now systematically and organizationally executed in accordance with production plans. The goal of quality management is to maintain quality continuously by ensuring a hygienic operating environment. This system, established in the United States in 1963 and first implemented in 1964, gained international recognition in 1968 when the World Health Organization (WHO) recommended it to various countries. Consequently, Germany adopted it in 1978, and Japan followed suit in 1980." Korea established GMP (Good Manufacturing Practice) regulations in 1977 and had been encouraging voluntary compliance within the industry. However, in 2007, Korea initiated the full implementation of GMP designation for medical devices, and for pharmaceuticals, the implementation of the GMP system began in 2008, starting with its application to new drugs.